Building an internationally oriented open regional innovation system : a paradox perspective

An open regional innovation system is often characterised by the firms' adoption of an open innovation strategy, which is closely linked to absorptive capacity. This study explores the effects of the firms' absorptive capacity on open regional innovation systems by investigating how regional firms respond to the development of an internationally oriented open regional innovation strategy. A living lap approach is adopted in this study based on the case of Sino-Finnish innovation capacity building in the Vaasa region in Finland. By addressing the tensions between exploitation and exploration innovation strategy, this research identifies three types of organisational paradox in relation to organisational absorptive capacity: (1) knowledge bases, (2) organisational policies, and (3) dominant logic. This paper also indicates the gradual evolution of the regional innovation system - the move from a centralised regional innovation system to a distributed regional innovation system, driven by the trend of globally distributed knowledge sharing.©2019 International Society for Professional Innovation Management (ISPIM)fi=vertaisarvioitu|en=peerReviewed

Monitoring of Tsunami/Earthquake Damages by Polarimetric Microwave Remote Sensing Technique

Polarization characterizes the vector state of EM wave. When interacting with polarized wave, rough natural surface often induces dominant surface scattering; building also presents dominant double-bounce scattering. Tsunami/earthquake causes serious destruction just by inundating the land surface and destroying the building. By analyzing the change of surface and double-bounce scattering before and after disaster, we can achieve a monitoring of damages. This constitutes one basic principle of polarimetric microwave remote sensing of tsunami/earthquake. The extraction of surface and double-bounce scattering from coherency matrix is achieved by model-based decomposition. The general four-component scattering power decomposition with unitary transformation (G4U) has been widely used in the remote sensing of tsunami/earthquake to identify surface and double-bounce scattering because it can adaptively enhance surface or double-bounce scattering. Nonetheless, the strict derivation in this chapter conveys that G4U cannot always strengthen the double-bounce scattering in urban area nor strengthen the surface scattering in water or land area unless we adaptively combine G4U and its duality for an extended G4U (EG4U). Experiment on the ALOS-PALSAR datasets of 2011 great Tohoku tsunami/earthquake demonstrates not only the outperformance of EG4U but also the effectiveness of polarimetric remote sensing in the qualitative monitoring and quantitative evaluation of tsunami/earthquake damages

Low-Cost Efficient Magnetic Adsorbent for Phosphorus Removal from Water

Adsorption using magnetic adsorbents makes the phosphorus removal from water simple and efficient. However, most of the reported magnetic adsorbents use chemically synthesized nanoparticles as magnetic cores, which are expensive and environmentally unfriendly. Replacing the nanomagnetic cores by cheap and green magnetic materials is essential for the wide application of this technique. In this paper, coal-fly-ash magnetic spheres (MSs) were processed to produce a cheap and eco-friendly magnetic core. A magnetic adsorbent, ZrO2 coated ball-milled MS (BMS@ZrO2), was prepared through a simple chemical precipitation method. Careful structural investigations indicate that a multipore structural amorphous ZrO2 layer has grown on the MS core. The specific surface area of BMS@ZrO2 is 48 times larger than that of the MS core. The highest phosphorus adsorption is tested as 16.47 mg g-1 at pH = 2. The BMS@ZrO2 adsorbent has a saturation magnetization as high as 33.56 emu g-1, enabling efficient magnetic separation. Zeta potential measurements and X-ray photoelectron spectroscopy analysis reveal that the phosphorus adsorption of BMS@ZrO2 is triggered by the electrostatic attraction and the ligand exchange mechanism. The BMS@ZrO2 adsorbent could be reused several times after proper chemical treatment

Osmotic Stress Induced Cell Death in Wheat Is Alleviated by Tauroursodeoxycholic Acid and Involves Endoplasmic Reticulum Stress–Related Gene Expression

Although, tauroursodeoxycholic acid (TUDCA) has been widely studied in mammalian cells because of its role in inhibiting apoptosis, its effects on plants remain almost unknown, especially in the case of crops such as wheat. In this study, we conducted a series of experiments to explore the effects and mechanisms of action of TUDCA on wheat growth and cell death induced by osmotic stress. Our results show that TUDCA: (1) ameliorates the impact of osmotic stress on wheat height, fresh weight, and water content; (2) alleviates the decrease in chlorophyll content as well as membrane damage caused by osmotic stress; (3) decreases the accumulation of reactive oxygen species (ROS) by increasing the activity of antioxidant enzymes under osmotic stress; and (4) to some extent alleviates osmotic stress–induced cell death probably by regulating endoplasmic reticulum (ER) stress–related gene expression, for example expression of the basic leucine zipper genes bZIP60B and bZIP60D, the binding proteins BiP1 and BiP2, the protein disulfide isomerase PDIL8-1, and the glucose-regulated protein GRP94. We also propose a model that illustrates how TUDCA alleviates osmotic stress–related wheat cell death, which provides an important theoretical basis for improving plant stress adaptation and elucidates the mechanisms of ER stress–related plant osmotic stress resistance

Phenotypic and functional alteration of CD45+ immune cells in the decidua of preeclampsia patients analyzed by mass cytometry (CyTOF)

Preeclampsia (PE) is a severe placenta-related pregnancy disease that has been associated with maternal systemic inflammation and immune system disorders. However, the distribution and functional changes in immune cells of the maternal–placental interface have not been well characterized. Herein, cytometry by time-of-flight mass spectrometry (CyTOF) was used to investigate the immune atlas at the decidua, which was obtained from four PE patients and four healthy controls. Six superclusters were identified, namely, T cells, B cells, natural killer (NK) cells, monocytes, granulocytes, and others. B cells were significantly decreased in the PE group, among which the reduction in CD27+CD38+ regulatory B cell (Breg)-like cells may stimulate immune activation in PE. The significantly increased migration of B cells could be linked to the significantly overexpressed chemokine C-X-C receptor 5 (CXCR5) in the PE group, which may result in the production of excessive autoantibodies and the pathogenesis of PE. A subset of T cells, CD11c+CD8+ T cells, was significantly decreased in PE and might lead to sustained immune activation in PE patients. NK cells were ultimately separated into four subsets. The significant reduction in a novel subset of NK cells (CD56-CD49a-CD38+) in PE might have led to the failure to suppress inflammation at the maternal–fetal interface during PE progression. Moreover, the expression levels of functional markers were significantly altered in the PE group, which also inferred that shifts in the decidual immune state contributed to the development of PE and might serve as potential treatment targets. This is a worthy attempt to elaborate the differences in the phenotype and function of CD45+ immune cells in the decidua between PE and healthy pregnancies by CyTOF, which contributes to understand the pathogenesis of PE, and the altered cell subsets and markers may inspire the immune modulatory therapy for PE

Microbial reduction and precipitation of vanadium (V) in groundwater by immobilized mixed anaerobic culture

Vanadium is an important contaminant impacted by natural and industrial activities. Vanadium (V) reduction efficiency as high as 87.0% was achieved by employing immobilized mixed anaerobic sludge as inoculated seed within 12 h operation, while V(IV) was the main reduction product which precipitated instantly. Increasing initial V(V) concentration resulted in the decrease of V(V) removal efficiency, while this index increased first and then decreased with the increase of initial COD concentration, pH and conductivity. High-throughput 16S rRNA gene pyrosequencing analysis indicated the decreased microbial diversity. V(V) reduction was realized through dissimilatory reduction process by significantly enhanced Lactococcus and Enterobacter with oxidation of lactic and acetic acids from fermentative microorganisms such as the enriched Paludibacter and the newly appeared Acetobacterium, Oscillibacter. This study is helpful to detect new functional species for V(V) reduction and constitutes a step ahead in developing in situ bioremediations of vanadium contamination. (C) 2015 Elsevier Ltd. All rights reserved.National Natural Science Foundation of China (NSFC) [41440025, 21307117]; Beijing Excellent Talent Training Project [2013D009015000003]; Beijing Higher Education Young Elite Teacher Project [YETP0657]SCI(E)[email protected]

Isolates of Liao Ning Virus from Wild-Caught Mosquitoes in the Xinjiang Province of China in 2005

Liao ning virus (LNV) is related to Banna virus, a known human-pathogen present in south-east Asia. Both viruses belong to the genus Seadornavirus, family Reoviridae. LNV causes lethal haemorrhage in experimentally infected mice. Twenty seven isolates of LNV were made from mosquitoes collected in different locations within the Xinjiang province of north-western China during 2005. These mosquitoes were caught in the accommodation of human patients with febrile manifestations, or in animal barns where sheep represent the main livestock species. The regions where LNV was isolated are affected by seasonal encephalitis, but are free of Japanese encephalitis (JE). Genome segment 10 (Seg-10) (encoding cell-attachment and serotype-determining protein VP10) and Seg-12 (encoding non-structural protein VP12) were sequenced for multiple LNV isolates. Phylogenetic analyses showed a less homogenous Seg-10 gene pool, as compared to segment 12. However, all of these isolates appear to belong to LNV type-1. These data suggest a relatively recent introduction of LNV into Xinjiang province, with substitution rates for LNV Seg-10 and Seg-12, respectively, of 2.29×10−4 and 1.57×10−4 substitutions/nt/year. These substitution rates are similar to those estimated for other dsRNA viruses. Our data indicate that the history of LNV is characterized by a lack of demographic fluctuations. However, a decline in the LNV population in the late 1980s - early 1990s, was indicated by data for both Seg-10 and Seg-12. Data also suggest a beginning of an expansion in the late 1990s as inferred from Seg-12 skyline plot

Generating unfair ratings to attack online rating systems

Many online voting systems have been developed to help users of the system to make informed decisions in nowadays. However, these systems may be attacked by different attack models. Meanwhile, the attack behavior is greatly influenced by the defense system used. Therefore, this project aims to investigate the detecting ability of each detection algorithm on each attack algorithm. In this paper, our main focus will be on the detection algorithms. For understanding and analyzing the results, this paper will involve the attack algorithms as well.Bachelor of Engineering (Computer Engineering